Mapping how early-life gut microbiota composition and function shape immune tolerance to dietary antigens, and leveraging engineered probiotics to enhance OIT efficacy and safety.
Prospective clinical cohort studies tracking how the neonatal gut microbiome is shaped by feeding, environment, and host genetics — and how these trajectories predict atopic disease risk.
Investigating how tick-associated gut microbiome alterations and alpha-gal sensitization converge to produce this newly recognized red-meat allergy, toward diagnostic and preventive strategies.
Exploring microbiome-mediated programming of airway immune responses, identifying early microbial signatures that predict childhood asthma development.